Prior Symptom Duration and Time to Onset of Improvement of CLD

• TIME TO FIRST IMPROVEMENT (WEEKS)

• PRIOR Sx

• DURATION 2 3 4 6 8 12

• <1 YR 68 4 20 8

• 1-3 YR 33 6 44 7 10

• >3 YR 26 6 37 12 17 2