Antibiotic treatment of Lyme

• Ann Rheum Dis 2005

• Am. Pen v Plac study 40 pts-55% resolved

• Outcome may depend on Bb species.

• Ceftriaxone v plac. 60pts 48%/10% improved.

• Study 16 pts refractory to antibiotics Ceft.Pr

• No response for 3/12 6 pts synovectomy

• 2-4 year history before spont resolution