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Table of contents
Dr. D. C. Owen BSc MB BCh LLM
A comparison of Lyme disease guidelines ILADS or IDSA?
OED definition of guideline
UK legal position with respect to guidelines
ILADS guidelines
IDSA guidelines
Cited references
Caveats
Adherence
Areas in which the guidelines are similar
Both claim to be evidence based
Both are consensus documents with multiple authors
Both express the view that early treatment of Lyme disease is important
Both sets of guidelines accept that coinfections may be important in some cases of Lyme disease.
Who treats Lyme disease?
Forms of Lyme disease - Terminology
Regarding persistent infection
Diagnosis -I
Diagnosis -II
Diagnosis -III
Neurologic Lyme - IDSA
Treatment of Lyme disease-I
Treatment of Lyme disease-II
Treatment of Lyme disease-III
Empiric treatment
Coinfections
Therapy for HGA
Therapy for Babesiosis
Therapy for Bartonella
Follow-up of patients
Therapy not recommended for Lyme disease (IDSA)
Slide 33
Post-Lyme syndrome
Proposed IDSA definition of Post-Lyme syndrome
Slide 36
Slide 37
Why is it that the IDSA and ILADS guidelines differ so greatly if they cite many references in common?
Slide 39
Slide 40
Difficulties in designing Lyme disease case controlled studies
What happens when there are two sets of guidelines which differ greatly?
Slide 43
Conclusions
Thank you