How to find a trial
The World Health Organisation maintains an on-line International Clinical Trials Registry Platform on which clinical trials are registered. The register allows for an internationally agreed set of criteria about clinical trials to be maintained. Clinical trials are those research studies investigating the effect of a health-related intervention.
Details of trials investigating interventions in Lyme disease, both in progress and completed, can be viewed via the search portal by entering “Lyme disease” in the search box. You will then be able to click on a link for any trial and find out further information.
Many of the trials have a link to ClinicalTrials.GOV under the US National Library of Medicine where there is further information, often much easier to read.
Recently registered trials
The following is a list of trials registered in 2019.
NL8224 PLEASE5+ – Long-term outcomes and quality of life of patients with symptoms attributed to Lyme borreliosis
NCT04148222 A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Lyme Disease
NCT04141969 A Novel Nutraceutical to Combat Post-Lyme Disease Syndrome
NCT04078841 Treating Post-Lyme Disease Syndrome With Acetogenins
NCT04038346 Symptomatic Management of Lyme Arthritis
NCT03981874 Peripheral Facial Paralysis Sequelae in Lyme Disease Among Children
EUCTR2018-003379-37-AT Lyme borreliosis study to evaluate immune response and to collect safety information of VLA15, which is a new vaccine candidate. study in healthy adults aged 18 to 65 years.
NCT03980015 Inflammatory Responses in Solitary and Multiple Erythema Migrans
NCT03970733 Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis
NCT03963635 Novel Diagnostics for Early Lyme Disease
NCT03958058 Tick-borne Encephalitis and Possible Borrelial Serology
NL7732 Validation of Cellular Tests for Lyme borreliosis
NCT03891667 Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease
EUCTR2018-003379-37-DE Lyme borreliosis study to evaluate immune response and to collect safety information of VLA15, which is a new vaccine candidate. Study in healthy adults aged 18 to 65 years.
NCT03873974 Performance Evaluation of the DualDur In Vitro Diagnostic System in the Diagnosis of Lyme Borreliosis
NCT03820999 An Intervention in a Primary Healthcare Setting to Reduce Lyme Neuroborreliosis Treatment Delay