How to find a trial

The World Health Organisation maintains an on-line International Clinical Trials Registry Platform on which clinical trials are registered. The register allows for an internationally agreed set of criteria about clinical trials to be maintained. Clinical trials are those research studies investigating the effect of a health-related intervention.

Details of trials investigating interventions in Lyme disease, both in progress and completed, can be viewed via the search portal by entering “Lyme disease” in the search box. You will then be able to click on a link for any trial and find out further information.

Many of the trials have a link to ClinicalTrials.GOV under the US National Library of Medicine where there is further information, often much easier to read.

Recently registered trials

The following is a list of trials registered in 2019.

NL8224 PLEASE5+ – Long-term outcomes and quality of life of patients with symptoms attributed to Lyme borreliosis

NCT04148222 A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Lyme Disease

NCT04141969 A Novel Nutraceutical to Combat Post-Lyme Disease Syndrome

NCT04078841 Treating Post-Lyme Disease Syndrome With Acetogenins

NCT04038346  Symptomatic Management of Lyme Arthritis

NCT03981874 Peripheral Facial Paralysis Sequelae in Lyme Disease Among Children

EUCTR2018-003379-37-AT Lyme borreliosis study to evaluate immune response and to collect safety information of VLA15, which is a new vaccine candidate. study  in healthy adults aged 18 to 65 years.

NCT03980015 Inflammatory Responses in Solitary and Multiple Erythema Migrans

NCT03970733 Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis

NCT03963635 Novel Diagnostics for Early Lyme Disease

NCT03958058 Tick-borne Encephalitis and Possible Borrelial Serology

NL7732 Validation of Cellular Tests for Lyme borreliosis

NCT03891667 Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease

EUCTR2018-003379-37-DE Lyme borreliosis study to evaluate immune response and to collect safety information of VLA15, which is a new vaccine candidate. Study in healthy adults aged 18 to 65 years.

NCT03873974 Performance Evaluation of the DualDur In Vitro Diagnostic System in the Diagnosis of Lyme Borreliosis

NCT03820999 An Intervention in a Primary Healthcare Setting to Reduce Lyme Neuroborreliosis Treatment Delay